CoRTecS

CYRCé

CYclotron pour la ReCherche et l'Enseignement

Physique | Biologie cellulaire | Imagerie | Biologie moléculaire | Biochimie | Génomique | Biologie systémique | Développement | Biologie structurale | Physiologie | Physiopathologie | Cardiologie | Pharmacologie | Endocrinologie | Cancer | Technologies médicales

The core facility

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Physique CYclotron pour la ReCherche et l'Enseignement

  • Core facility network


  • Scientifical Manager
     Ziad EL BITAR
  • Technical Manager
     Michel PELLLICIOLI
  • UMR 7178 - IPHC / Institut pluridisciplinaire Hubert Curien
  • CNRS, UNIVERSITE DE STRASBOURG
  • Cronenbourg Schiltigheim
  • Monosite
  • Service delivery
    • to the academic community
    • to the socio-economic world
  • Collaborations of research
    • with the academic community
    • to the socio-economic world
  • Affiliated institution of administrative supervision
    • CNRS
    • UNIVERSITE DE STRASBOURG
CYRCé

Molecular imaging is an essential tool to study disease development, treatments (drugs, irradiation), biological processes,… in vivo, non-invasively. Thanks to their very high sensitivities, Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) play a central role in this research domain. To perform PET and SPECT imaging we need an isotope (positron emitter or gamma emitter) combined to a molecule of interest, an animal model and a PET or SPECT system. In addition to the imaging facilities, we have two proton beam line (one for detector irradiation and one for biological sample irradiation).

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Expertises

Scientific expertise

  • Isotopes production
  • Small animal imaging
  • Proton irradiation (on materials or biological samples)
  • Cell cultur
  • Molecular biology

Technical expertise

  • Targets irradiation, proton beam managment and design, xenografted mouse model
  • PET imaging
  • CT imaging, biodistribution evaluation

Resources

Main equipments

  • Cyclotron TR24 from ACSI, µTEP-CT IRIS from INVISCAN, homemade irradiation beam lines, SL300 from Hidex

Ministerial autorisations to experiment

  • Autorisation nominative d'expérimenter sur l'animal
  • Agrément d'utilisation d'animaux à des fins scientifiques
  • Agrément d'utilisation en milieu confiné d'organismes génétiquement modifiés

Specific rooms

  • Laboratoire L2
  • Animalerie A2

Software resources / Data bases

  • Pmod, osirix

Recent collaborative projects

RpPET

RpPET

Macroscopic study of the efficiency of protontherapy using PET imaging

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FET as a translational radiotracer in insulinoma

FET as a translational radiotracer in insulinoma

This translational project highlighted the interest of FET radiotracer in insulinoma in vivo and in Human.

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Core facility partners