Détail

La plateforme

Plant Imaging & Mass Spectrometry

Directeur-trice de la plateforme Dimitri HEINTZ
Directeur-trice scientifique Dimitri HEINTZ
Directeur-trice technique DIMITRI HEINTZ

UPR 2357 - IBMP / Institut de biologie moléculaire des plantes
CNRS

Site web de la plateforme

Campus centre : Esplanade
Monosite

Prestations de services
- à la communauté académique
- au monde socio-économique

Collaborations de recherche
- avec la communauté académique
- avec le monde socio-économique

Tutelles de rattachement

CNRS

PIMS platform activity is focused on metabolomics, which is the analysis of small bioactive molecules (<1,000 Da), as lipids, sugars, amino acids, nucleic acids but also xenobiotics such as drugs, pesticides and other industrial pollutants. These analyses are made in biological samples (plants, animals, human, bacteria, water, soil) for IBMp teams, but also for other institutes, laboratories or collaborators in France, Europe and internationally. The platform performs the targeted analysis of molecules of interest, even in small quantities, and the non-targeted analysis for the exploration of metabolism. The platform masters imaging mass spectrometry (IMS), which allows the localisation of metabolites on intact tissues in a spatial and temporal way, using targeted or non-targeted approaches.

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Certifications et accréditations

Documents de la plateforme

Expertises

Expertise scientifique

Targeted and non-targeted metabolomics
Targeted and non-targeted lipidomics
Targeted and non-targeted environmental metabolomics
MALDI imaging
Liquid chromatography
Gas chromatography
Sample preparation
Histology
Data processing
Statistics
Training
Teaching
Scientific communication and popularization: written press, radio, oral presentations in congresses and seminars, technical and popularization videos, scientific publications

Expertise technique

Development of chromatography and mass spectrometry methods
Metabolism analysis of plants, animals, human, microbes ...
Lipid analysis of plants, animals, human, microbes...
Micropollutants analysis (pesticides, drugs, plastics...)
Histological cuts
Quantification of metabolites
Targeted analysis of metabolites
Small molecules analysis in soils
Data processing
Non-targeted analysis of metabolites

Ressources

Principaux équipements

LC-UV-MS/MS TQ Waters Quattro premier
LC-UV-MS/MS TQ Bruker EvoQ
GC-MS/MS-TQ Bruker SCION
LC-MS/MS Q-TOF Bruker Impact II
HPLC DAD electrospray simple quadripôle with fraction collector (Waters)
ESI-MALDI-FT-ICR Bruker SolariX
HTX M5 Sprayer
Bruker Image Prep
LESA ADVION
Thermo Cryomicrotome
Thermo Speed vac (1)
Thermo Speed vac (2)

Autorisations ministérielles d'expérimenter

Agrément d'utilisation en milieu confiné d'organismes génétiquement modifiés

Autres locaux

Dedicated data processing room
Histology laboratory

Ressources logicielles / bases de données

MS Workstation, MS DataReview, XCMS, MetaboAnalyst, NIST, Wiley, Maurer Pfleger, GOLM, Internal databases, MassLynx, QuanLynx, Hystar, Chromeleon, MSData Review, Data Analysis, MetaboAnalyst, Otof Control, DataAnalysis, MetaboScape, MetabolitePredict, Library Editor, MetFrag, IsotopePattern, ChemRICH, Cytoscape, MetExplore, PubChem, Identifier Exchange Service, MsConvert (Proteowizard), Kegg, METLIN, HMDB, FoodDB, LipidMaps, SwissLipids, KNApSAcK, PlantCyc, Natural products atlas (NPA), ECMDB, YMDB, PhenolExplorer, Norman, FTMSControl, FlexImaging, SCiLS, Metaspace, MSworkStation, MSdatareview